RVD-Hpα

Name: RVD-Hpα
Brand: Tocris Bioscience
SKU: 3744

Tocris Bioscience, part of Bio-Techne | Catalog # 3744

COA / SDS

Selective CB1 agonist; also CB2 PAM

Discontinued Product

3744 has been discontinued. View all Cannabinoid R1/CB1 Agonists products.

Key Product Details

Description:	Selective CB₁ agonist; also CB₂ PAM
Alternative Names:	Pepcan-12
Molecular Weight:	1424.66

View Full Technical Details for RVD-Hpα

Technical Data
Citations

Biological Activity for RVD-Hpα

RVD-Hpα is a N-terminally extended form of human hemopressin that acts as a selective CB₁ receptor agonist. Increases intracellular Ca²⁺ levels in cells expressing CB₁ receptors in vitro. Also high affinity CB₂ positive allosteric modulator (K_i = 50 nM).

Technical Data for RVD-Hpα

M. Wt	1424.66
Formula	C₆₅H₁₀₅N₁₉O₁₇
Single Letter Sequence	RVDPVNFKLLSH
Storage	Store at -20°C
CAS Number	1193362-76-3
PubChem ID	90488874
InChi Key	CSDQEWILNKOWRN-WSDCEOHFSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for RVD-Hpα

References are publications that support the biological activity of the product.

Khurana Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology 2017 PMID: 28527758
Gomes Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 2009 PMID: 19380512

RVD-Hpα

Tocris Bioscience, part of Bio-Techne | Catalog # 3744

Key Product Details

Biological Activity for RVD-Hpα

Technical Data for RVD-Hpα

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for RVD-Hpα

Product Documents for RVD-Hpα

COA

Certificate of Analysis

SDS

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