RuBi-GABA
Tocris Bioscience, part of Bio-Techne | Catalog # 3400
Caged GABA; excitable at visible wavelengths
Key Product Details
Description
Caged GABA; excitable at visible wavelengths
Product Description
RuBi-GABA is a ruthenium-bipyridine-triphenylphosphine caged GABA (Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.Licensing Information
Sold under licence from Columbia UniversityProduct Specifications
Molecular Weight
922.80
Formula
C42H39F6N5O2P2Ru
Storage
Store at -20°C
Chemical Name
(bis(2,2'-Bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex
CAS Number
1028141-88-9
PubChem ID
117071637
InChI Key
YMUDUHPMAODLNP-UHFFFAOYSA-N
SMILES
[Ru++].NCCCC([O-])=O.F[P-](F)(F)(F)(F)F.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1.C1=CC=C(C=C1)P(C1=CC=CC=C1)C1=CC=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
Please refer to these solubility guidelines for RuBi-GABA (Cat. No. 3400).
Calculators
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Background References
References are publications that support the biological activity of the product.
- Rial Verde Photorelease of GABA with visible light using an inorganic caging group. Front.Neural Circuits 2008 PMID: 18946542
- Zayat A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 2003 PMID: 12537482
Product Specific Notices for RuBi-GABA
For research use only
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