GABA

Tocris Bioscience, part of Bio-Techne | Catalog # 0344

COA / SDS

Endogenous agonist

Key Product Details

Description:	Endogenous agonist
Chemical Name:	γ-Aminobutyric acid
Molecular Weight:	103.12

View Full Technical Details for GABA

Technical Data
Citations

Biological Activity for GABA

GABA is a GABA receptor agonist and endogenous inhibitory neurotransmitter. Caged RuBi GABA is also available (Cat. No. 3400).

Technical Data for GABA

M. Wt	103.12
Formula	C₄H₉NO₂
Storage	Store at RT
CAS Number	56-12-2
PubChem ID	119
InChi Key	BTCSSZJGUNDROE-UHFFFAOYSA-N
Smiles	NCCCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for GABA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	10.31	100

Preparing Stock Solutions for GABA

The following data is based on the product molecular weight 103.12.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	9.70 mL	48.49 mL	96.97 mL
5 mM	1.94 mL	9.70 mL	19.39 mL
10 mM	0.97 mL	4.85 mL	9.70 mL
50 mM	0.19 mL	0.97 mL	1.94 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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References for GABA

References are publications that support the biological activity of the product.

Malcangio and Bowery GABA and its receptors in the spinal cord. TiPS 1996 PMID: 9014500
Decavel and van den Pol GABA: a dominant transmitter in the hypothalamus. J.Comp.Neurol. 1990 PMID: 2081813
Johnston GABA_C receptors: relatively simple transmitter-gated ion channels? TiPS 1996 PMID: 8885697
Curtis GABA, bicuculline and central inhibition. Nature 1970 PMID: 4393081