(RS)-(Tetrazol-5-yl)glycine
Tocris Bioscience, part of Bio-Techne | Catalog # 0312
Highly potent NMDA agonist
Product Description
(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA.Product Specifications
Molecular Weight
143.10
Formula
C3H5N5O2
Storage
Store at RT
Purity
≥98% (HPLC)
CAS Number
138199-51-6
PubChem ID
126383
InChI Key
UKBRUIZWQZHXFL-UHFFFAOYSA-N
SMILES
NC(C(O)=O)C1=NN=NN1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 50 |
Preparing Stock Solutions
for (RS)-(Tetrazol-5-yl)glycine
The following data is based on the product molecular weight 143.10
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 13.98 mL | 69.88 mL | 139.76 mL |
| 2.5 mM | 2.80 mL | 13.98 mL | 27.95 mL |
| 5 mM | 1.40 mL | 6.99 mL | 13.98 mL |
| 25 mM | 0.28 mL | 1.40 mL | 2.80 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Moroni NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn Schmiedebergs Arch.Pharmacol. 1995 PMID: 7543185
- Schoepp D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol. 1991 PMID: 1686860
- Arnt Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol. 1995 PMID: 8575516
Product Specific Notices for (RS)-(Tetrazol-5-yl)glycine
For research use only
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