RBC8

Name: RBC8
Brand: Tocris Bioscience
SKU: 5411

Tocris Bioscience, part of Bio-Techne | Catalog # 5411

Citations (2)

COA / SDS

RalA and RalB inhibitor

Discontinued Product

5411 has been discontinued. View all Ras GTPase Inhibitors products.

Key Product Details

Description:	RalA and RalB inhibitor
Chemical Name:	6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile
Purity:	≥98% (HPLC)
Molecular Weight:	424.45

View Full Technical Details for RBC8

Technical Data
Citations

Biological Activity for RBC8

RBC8 is a RalA and RalB GTPase inhibitor (EC₅₀ ~3.5 μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable.

Technical Data for RBC8

M. Wt	424.45
Formula	C₂₅H₂₀N₄O₃
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	361185-42-4
PubChem ID	6626226
InChi Key	CLMQBVUFKIKYLU-UHFFFAOYSA-N
Smiles	NC1=C(C#N)C(C5=C(OC)C=CC(OC)=C5)C(C(C3=CC=C(C=CC=C4)C4=C3)=NN2)=C2O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for RBC8

References are publications that support the biological activity of the product.

Yan Discovery and characterization of small molecules that target the GTPase Ral. Nature 2014 PMID: 25219851

RBC8

Tocris Bioscience, part of Bio-Techne | Catalog # 5411

Key Product Details

Biological Activity for RBC8

Technical Data for RBC8

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for RBC8

Product Documents for RBC8

COA

Certificate of Analysis

SDS

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