(R)-3,4-DCPG
Tocris Bioscience, part of Bio-Techne | Catalog # 1395
AMPA antagonist/weak NMDA antagonist
Discontinued Product
1395 has been discontinued.
View all iGluR Antagonists products.
Product Description
(R)-3,4-DCPG is a AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors.Racemate and S-enantiomer also available.
Product Specifications
Molecular Weight
239.18
Formula
C10H9NO6
Storage
Desiccate at RT
Purity
≥96% (HPLC)
Chemical Name
(R)-3,4-Dicarboxyphenylglycine
CAS Number
201730-10-1
PubChem ID
6604849
InChI Key
IJVMOGKBEVRBPP-SSDOTTSWSA-N
SMILES
N[C@@]([H])(C(O)=O)C1=CC(C(O)=O)=C(C(O)=O)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 100 |
Preparing Stock Solutions
for (R)-3,4-DCPG
The following data is based on the product molecular weight 239.18
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.18 mL | 20.90 mL | 41.81 mL |
| 5 mM | 0.84 mL | 4.18 mL | 8.36 mL |
| 10 mM | 0.42 mL | 2.09 mL | 4.18 mL |
| 50 mM | 0.08 mL | 0.42 mL | 0.84 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Thomas Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 1997 PMID: 9455991
- Moldrich Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 2001 PMID: 11311902
Product Specific Notices for (R)-3,4-DCPG
For research use only
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