(+)-Bicuculline

Tocris Bioscience, part of Bio-Techne | Catalog # 0130

Potent GABAA antagonist
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Key Product Details

Description

Potent GABAA antagonist

View all GABA-A Receptor Antagonists »

Product Description

(+)-Bicuculline is a classical GABAA antagonist.

Methoiodide Salt, Methobromide Salt and Methochloride Salt also available.

Product Specifications

Molecular Weight

367.36

Formula

C20H17NO6

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

[R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one

CAS Number

485-49-4

PubChem ID

10237

InChI Key

IYGYMKDQCDOMRE-ZWKOTPCHSA-N

SMILES

[H][C@](C(C=CC6=C5OCO6)=C5C(O4)=O)4[C@]2([H])C1=CC3=C(OCO3)C=C1CCN2C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.74 100

Preparing Stock Solutions for (+)-Bicuculline

The following data is based on the product molecular weight 367.36

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.72 mL 13.61 mL 27.22 mL
5 mM 0.54 mL 2.72 mL 5.44 mL
10 mM 0.27 mL 1.36 mL 2.72 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for (+)-Bicuculline

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (+)-Bicuculline

For research use only

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