(-)-Bicuculline methobromide

Tocris Bioscience, part of Bio-Techne | Catalog # 0109

GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
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Key Product Details

Description

GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)

View all GABA-A Receptor Antagonists »

Product Description

(-)-Bicuculline methobromide is a methobromide salt of (+)-bicuculline. Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

Methoiodide Salt and Methochloride Salt also available.

Product Specifications

Molecular Weight

462.30

Formula

C21H20BrNO6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

[R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide

CAS Number

66016-70-4

PubChem ID

6852386

InChI Key

BWXCECYGGMGBHD-GRTNUQQKSA-M

SMILES

[H][C@](C(C=CC6=C5OCO6)=C5C(O4)=O)4[C@]2([H])C1=CC3=C(OCO3)C=C1CC[N+](C)2C.[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 23.11 50

Preparing Stock Solutions for (-)-Bicuculline methobromide

The following data is based on the product molecular weight 462.30

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.33 mL 21.63 mL 43.26 mL
2.5 mM 0.87 mL 4.33 mL 8.65 mL
5 mM 0.43 mL 2.16 mL 4.33 mL
25 mM 0.09 mL 0.43 mL 0.87 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (-)-Bicuculline methobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (-)-Bicuculline methobromide

For research use only

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