Okadaic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 1136

Protein phosphatase 1 and 2A inhibitor
Discontinued Product
1136 has been discontinued. View all Protein Ser/Thr Phosphatase Inhibitors products.

Key Product Details

Description

Protein phosphatase 1 and 2A inhibitor

View all Protein Ser/Thr Phosphatase Inhibitors »

Product Description

Okadaic acid is a potent inhibitor of protein phosphatase 1 (IC50 = 3 nM) and protein phosphatase 2A (IC50 = 0.2-1 nM). Displays > 100,000,000-fold selectivity over PP2B and PP2C. Tumor promoter. Shown to activate atypical protein kinase C in adipocytes.

Okadaic acid ammonium salt (Cat. No. 9012) also available.

Product Specifications

Molecular Weight

805.01

Formula

C44H68O13

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

9,10-Deepithio-9,10-didehydroacanthifolicin

CAS Number

78111-17-8

PubChem ID

90479758

InChI Key

QNDVLZJODHBUFM-WFXQOWMNSA-N

SMILES

[H][C@]1(CC(C)=C[C@@]2(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]2O)O1)[C@H](C)\C=C\[C@H]1CC[C@@]2(CC[C@@]3([H])O[C@]([H])([C@@H](O)C[C@H](C)[C@@]4([H])O[C@@]5(CCCCO5)CC[C@H]4C)C(=C)[C@@H](O)[C@]3([H])O2)O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40

Preparing Stock Solutions for Okadaic acid

The following data is based on the product molecular weight 805.01

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 2.48 mL 12.42 mL 24.84 mL
2.5 mM 0.50 mL 2.48 mL 4.97 mL
5 mM 0.25 mL 1.24 mL 2.48 mL
25 mM 0.05 mL 0.25 mL 0.50 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Okadaic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Okadaic acid

For research use only

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