NSC 632839 hydrochloride

Name: NSC 632839 hydrochloride
Brand: Tocris Bioscience
SKU: 2647
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2647

(1)

Citations (5)

COA / SDS

Inhibitor of ubiquitin isopeptidase activity

Discontinued Product

2647 has been discontinued. View all Deubiquitinating Enzyme Inhibitors products.

Key Product Details

Description:	Inhibitor of ubiquitin isopeptidase activity
Alternative Names:	F6
Chemical Name:	3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	339.86

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Technical Data
Citations / Reviews (1)

Biological Activity for NSC 632839 hydrochloride

NSC 632839 hydrochloride is an inhibitor of ubiquitin isopeptidase activity that displays no effect on the proteolytic activity of the proteasome. Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC₅₀ values are 15.65 and 16.23 μM in E1A and E1A/C9CN cells respectively).

Technical Data for NSC 632839 hydrochloride

M. Wt	339.86
Formula	C₂₁H₂₁NO.HCl
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	157654-67-6
PubChem ID	5351362
InChi Key	ZOKZLTXPTLIWOJ-BYCVLTJGSA-N
Smiles	O=C(/C(CNC3)=C/C2=CC=C(C)C=C2)/C3=C/C1=CC=C(C)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NSC 632839 hydrochloride

References are publications that support the biological activity of the product.

Aleo Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis. Cancer Res. 2006 PMID: 16982768

NSC 632839 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2647

Key Product Details

Biological Activity for NSC 632839 hydrochloride

Technical Data for NSC 632839 hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for NSC 632839 hydrochloride

Product Documents for NSC 632839 hydrochloride

COA

Certificate of Analysis

SDS

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