Nα-Methylhistamine dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0573

Non-selective H3 agonist
Discontinued Product
0573 has been discontinued. View all Histamine H3 Receptor Agonists products.

Key Product Details

Description

Non-selective H3 agonist

View all Histamine H3 Receptor Agonists »

Product Description

Nα-Methylhistamine dihydrochloride is a potent histamine agonist, particularly at H3 receptors (potency relative to histamine is 81, 185, and 270% at H1, H2 and H3 respectively). Also displays agonist properties at H4 receptors to which it binds with moderate affinity (Ki = 23 nM).

Product Specifications

Molecular Weight

198.09

Formula

C6H11N3.2HCl

Storage

Desiccate at RT

Chemical Name

N-Methyl-1H-imidazole-4-ethanamine dihydrochloride

CAS Number

16503-22-3

PubChem ID

16078977

InChI Key

AYUQICXJAMPXPF-UHFFFAOYSA-N

SMILES

Cl.Cl.CNCCC1=CNC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 19.81 100

Preparing Stock Solutions

The following data is based on the product molecular weight 198.09

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.05 mL 25.24 mL 50.48 mL
5 mM 1.01 mL 5.05 mL 10.10 mL
10 mM 0.50 mL 2.52 mL 5.05 mL
50 mM 0.10 mL 0.50 mL 1.01 mL

Calculators

Molarity Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices

For research use only

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