MRS 1334

Tocris Bioscience, part of Bio-Techne | Catalog # 1385

Potent, highly selective hA3 antagonist
Discontinued Product
1385 has been discontinued. View all Adenosine A3 Receptor Antagonists products.

Key Product Details

Description

Potent, highly selective hA3 antagonist

View all Adenosine A3 Receptor Antagonists »

Product Description

MRS 1334 is a potent and highly selective antagonist for the human adenosine A3 receptor. Ki values are 2.69 nM at hA3, and > 100 μM at rat A1 and rat A2A receptors.

Licensing Information

Sold with the permission of the NIH, US Patent 60/029,855

Product Specifications

Molecular Weight

522.56

Formula

C31H26N2O6

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

1,4-Dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-3,5-pyridinedicarboxylic acid 3-ethyl-5-[(3-nitrophenyl)methyl] ester

CAS Number

192053-05-7

PubChem ID

4519822

InChI Key

QFLOJAMZLQXHFS-UHFFFAOYSA-N

SMILES

CCOC(=O)C1=C(C)NC(C2=CC=CC=C2)=C(C1C#CC1=CC=CC=C1)C(=O)OCC1=CC=C(C=C1)N(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 52.26 100

Preparing Stock Solutions for MRS 1334

The following data is based on the product molecular weight 522.56

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.91 mL 9.57 mL 19.14 mL
5 mM 0.38 mL 1.91 mL 3.83 mL
10 mM 0.19 mL 0.96 mL 1.91 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for MRS 1334

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MRS 1334

For research use only

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