ML 239

Name: ML 239
Brand: Tocris Bioscience
SKU: 4829
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4829

(1)

COA / SDS

Breast cancer stem cell inhibitor

Discontinued Product

4829 has been discontinued. View all Stem Cell Signaling Compounds products.

Key Product Details

Description:	Breast cancer stem cell inhibitor
Chemical Name:	2-(2,4,6-Trichlorophenoxy)acetic acid (2E)-2-(1H-pyrrol-2-ylmethylene)hydrazide
Purity:	≥98% (HPLC)
Molecular Weight:	346.6

View Full Technical Details for ML 239

Technical Data
Citations / Reviews (1)

Biological Activity for ML 239

ML 239 is a breast cancer stem cell inhibitor (IC₅₀ = 1.16 μM). Exhibits 24-fold selectivity for breast cancer stem cells over normal mammary epithelial cells. Also cytotoxic towards MDA-MB-231 breast cancer cells in vitro.

Technical Data for ML 239

M. Wt	346.6
Formula	C₁₃H₁₀Cl₃N₃O₂
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	1378872-36-6
PubChem ID	90488975
InChi Key	WOCCOXNODBCCGK-UHFFFAOYSA-N
Smiles	ClC1=C(OCC(N/N=C/C2=CC=CN2)=O)C(Cl)=CC(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ML 239

References are publications that support the biological activity of the product.

Germain Identification of a selective small molecule inhibitor of breast cancer stem cells. Bioorg.Med.Chem.Lett. 2012 PMID: 22503247
Carmody Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells. J.Biol.Chem. 2012 PMID: 22941295

ML 239

Tocris Bioscience, part of Bio-Techne | Catalog # 4829

Key Product Details

Biological Activity for ML 239

Technical Data for ML 239

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for ML 239

Product Documents for ML 239

COA

Certificate of Analysis

SDS

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