M871
Tocris Bioscience, part of Bio-Techne | Catalog # 2698
Selective GAL2 antagonist
Key Product Details
Description
Selective GAL2 antagonist
Alternative Names
Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide
Product Description
M871 is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists.Product Specifications
Molecular Weight
2287.64
Formula
C108H163N27O28
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
908844-75-7
PubChem ID
90477989
InChI Key
BHKXASDHGWBINL-ZEHYZEGSSA-N
SMILES
[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Sollenburg M871 - a novel peptide antagonist selectively recognizing the galanin receptor type 2. Int.J.Pept.Res.Ther.
- Jimenez-Andrade Activation of peripheral galanin receptors: differential effects on nociception. Pharmacol.Biochem.Behav. 2006 PMID: 16996122
Product Specific Notices for M871
For research use only
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