[Lys5,MeLeu9,Nle10]-NKA(4-10)
Tocris Bioscience, part of Bio-Techne | Catalog # 3228
Selective NK2 agonist
Discontinued Product
3228 has been discontinued.
View all NK2 Receptor Agonists products.
Product Description
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).Product Specifications
Molecular Weight
804.00
Formula
C39H65N9O9
Storage
Desiccate at -20°C
CAS Number
137565-28-7
PubChem ID
10417908
InChI Key
FIBMQAYBIOYAKI-HLYNNXGTSA-N
SMILES
[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](CCCC)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Matuszek An investigation of tachykinin NK2 receptor subtypes in the rat. Eur.J.Pharmacol. 1998 PMID: 9718274
- Burcher Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomet. and in diverticular disease and ulcerative colitis. J.Pharmacol.Exp.Ther. 2008 PMID: 17959748
- Chassaing Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 1991 PMID: 1658676
Product Specific Notices for [Lys5,MeLeu9,Nle10]-NKA(4-10)
For research use only
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