Lac-Phe
Tocris Bioscience, part of Bio-Techne | Catalog # 7942
Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise
Key Product Details
Description
Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise
Product Description
Lac-Phe is a metabolite generated from lactate and phenylalanine by cytosolic non-specific dipeptidase (CNDP2) during intense exercise. Lac-Phe reduces food intake in diet-induced obese mice without affecting movement or energy expenditure. When administrated chronically, Lac-Phe decreases adiposity and body weight and improves glucose homeostasis.Product Specifications
Molecular Weight
237.26
Formula
C12H15NO4
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine
CAS Number
183241-73-8
PubChem ID
11075454
InChI Key
IIRJJZHHNGABMQ-WPRPVWTQSA-N
SMILES
C[C@H](O)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 23.73 | 100 |
Preparing Stock Solutions
for Lac-Phe
The following data is based on the product molecular weight 237.26
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.21 mL | 21.07 mL | 42.15 mL |
| 5 mM | 0.84 mL | 4.21 mL | 8.43 mL |
| 10 mM | 0.42 mL | 2.11 mL | 4.21 mL |
| 50 mM | 0.08 mL | 0.42 mL | 0.84 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Li An exercise-inducible metabolite that suppresses feeding and obesity. Nature 2022 PMID: 35705806
Product Specific Notices for Lac-Phe
For research use only
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