L-CCG-l
Tocris Bioscience, part of Bio-Techne | Catalog # 0333
Potent group II mGlu agonist
Key Product Details
Description
Potent group II mGlu agonist
Alternative Names
(2S,3S,4S)-CCG
Product Description
L-CCG-l is a potent group II metabotropic glutamate receptor agonist. More active than glutamate or (±)-trans-ACPD (Cat. No. 0187).Product Specifications
Molecular Weight
159.14
Formula
C6H9NO4
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine
CAS Number
117857-93-9
PubChem ID
5310956
InChI Key
GZOVEPYOCJWRFC-HZLVTQRSSA-N
SMILES
N[C@]([H])(C(O)=O)[C@@]([H])(C1)[C@]1([C@@](O)=O)[H]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 100 |
Preparing Stock Solutions
for L-CCG-l
The following data is based on the product molecular weight 159.14
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.28 mL | 31.42 mL | 62.84 mL |
| 5 mM | 1.26 mL | 6.28 mL | 12.57 mL |
| 10 mM | 0.63 mL | 3.14 mL | 6.28 mL |
| 50 mM | 0.13 mL | 0.63 mL | 1.26 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wright and Schoepp Differentiation of group 2 and group 3 metabotropic glutamate receptor cAMP responses in the rat hippocampus. Eur.J.Pharmacol. 1996 PMID: 8666060
- Hayashi Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 1992 PMID: 1330184
- Shinozaki Potent NMDA-like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord. Br.J.Pharmacol. 1989 PMID: 2692753
- Brabet Comparative effect of L-CCG-I, DCG-IV and γ-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes. Neuropharmacology 1998 PMID: 9833633
Product Specific Notices for L-CCG-l
For research use only
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