L-703,664 succinate
Tocris Bioscience, part of Bio-Techne | Catalog # 2640
Selective 5-HT1D agonist
Discontinued Product
2640 has been discontinued.
View all 5-HT1D Receptor Agonists products.
Product Description
L-703,664 succinate is a 5-HT1D receptor agonist that displays selectivity over other 5-HT receptor subtypes (pIC50 values are 7.2, 6.1, < 5.0 and < 5.0 for 5-HT1D, 5-HT1A, 5-HT2A and 5-HT3 respectively) and other receptors (pIC50 < 5.0 for adenosine, adrenergic, excitatory amino acids, dopamine, histamine, muscarinic, nicotinic and opiate receptors).Licensing Information
Sold with the permission of Merck, Sharpe and Dohme Ltd.Product Specifications
Molecular Weight
454.54
Formula
C16H24N4O2S.C4H6O4
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
N,N-Dimethyl-5-[(5-methyl-1,1-dioxodo-1,2,5-thiadiazolidin-2-yl)methyl]-1H-indole-3-ethanamine succinate
CAS Number
144776-01-2
PubChem ID
90488774
InChI Key
WLXRLNXDMGIORD-UHFFFAOYSA-N
SMILES
O=S1(N(CCN1C)CC2=CC=C(NC=C3CCN(C)C)C3=C2)=O.O=C(CCC(O)=O)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 22.73 | 50 | |
| DMSO | 45.45 | 100 |
Preparing Stock Solutions
for L-703,664 succinate
The following data is based on the product molecular weight 454.54
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.20 mL | 11.00 mL | 22.00 mL |
| 5 mM | 0.44 mL | 2.20 mL | 4.40 mL |
| 10 mM | 0.22 mL | 1.10 mL | 2.20 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.44 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for L-703,664 succinate
For research use only
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