Ketamine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3131

Non-competitive NMDA receptor antagonist
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3131/2G
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Key Product Details

Description

Non-competitive NMDA receptor antagonist

View all NMDA Receptor Antagonists »

Product Description

Ketamine hydrochloride is a non-competitive NMDA receptor antagonist (EC50 values are 13.6 and 17.6 μM for GluN1/GluN2A (formally NR1 and NR2A, respectively) and GluN1/GluN2B (formally NR1 and NR2B, respectively) subunit combinations respectively). Dissociative anesthetic.

S-enantiomer and Active metabolite also available.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions. .

Product Specifications

Molecular Weight

274.19

Formula

C13H16ClNO.HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride

CAS Number

1867-66-9

PubChem ID

15851

InChI Key

VCMGMSHEPQENPE-UHFFFAOYSA-N

SMILES

O=C1C(C2=CC=CC=C2Cl)(NC)CCCC1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 27.42 100

Preparing Stock Solutions for Ketamine hydrochloride

The following data is based on the product molecular weight 274.19

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.65 mL 18.24 mL 36.47 mL
5 mM 0.73 mL 3.65 mL 7.29 mL
10 mM 0.36 mL 1.82 mL 3.65 mL
50 mM 0.07 mL 0.36 mL 0.73 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ketamine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ketamine hydrochloride

For research use only

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