Grifolic acid
Tocris Bioscience, part of Bio-Techne | Catalog # 4581
Selective partial FFA4 (GPR120) agonist
Discontinued Product
4581 has been discontinued.
View all Free Fatty Acid Receptor Agonists products.
Key Product Details
Description
Selective partial FFA4 (GPR120) agonist
Product Description
Grifolic acid is a selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca2+]i responses in cells expressing GPR120, but not those expressing GPR40.Product Specifications
Molecular Weight
372.50
Formula
C23H32O4
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoic acid
CAS Number
80557-12-6
PubChem ID
9976563
InChI Key
QPIZDZGIXDKCRC-JTCWOHKRSA-N
SMILES
OC1=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)C(O)=C(C(O)=O)C(C)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.25 | 100 |
Preparing Stock Solutions
for Grifolic acid
The following data is based on the product molecular weight 372.50
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.68 mL | 13.42 mL | 26.85 mL |
| 5 mM | 0.54 mL | 2.68 mL | 5.37 mL |
| 10 mM | 0.27 mL | 1.34 mL | 2.68 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.54 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Sun Structure-activity relationships of GPR120 agonists based on a docking simulation. Mol.Pharmacol. 2010 PMID: 20685848
- Hara Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch.Pharmacol. 2009 PMID: 19471906
Product Specific Notices for Grifolic acid
For research use only
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