G-Protein antagonist peptide is a substance P-related peptide that inhibits binding of G proteins to their receptors. Competitively and reversibly inhibits M₂ muscarinic receptor activation of G_i or G_o and inhibits G_s activation by β-adrenoceptors.

Product Specifications

Molecular Weight

1093.27

Formula

C₅₇H₆₄N₁₂O₉S

Storage

Desiccate at -20°C

CAS Number

143675-79-0

PubChem ID

71308571

InChI Key

WSYRBHQWMXTCHQ-SFIKJRKMSA-N

SMILES

[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in DMSO

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Background References

References are publications that support the biological activity of the product.

Mukai G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 1992 PMID: 1379592

G-Protein antagonist peptide

Tocris Bioscience, part of Bio-Techne | Catalog # 1931

Key Product Details

Description

Alternative Names

View all G Protein (Heterotrimeric) Inhibitors »

Product Description