Endomorphin-1
Tocris Bioscience, part of Bio-Techne | Catalog # 1055
Potent and selective μ agonist
Discontinued Product
1055 has been discontinued.
View all mu Opioid Receptor Agonists products.
Key Product Details
Description
Potent and selective μ agonist
Product Description
Endomorphin-1 is a endogenous peptide with an exceptionally high affinity (Ki = 360 pM) and selectivity for μ opioid receptors (4000- and 15000-fold preference over δ and κ respectively).Product Specifications
Molecular Weight
610.67
Formula
C34H38N6O5
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
189388-22-5
PubChem ID
5311080
InChI Key
ZEXLJFNSKAHNFH-SYKYGTKKSA-N
SMILES
[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 0.6mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Zadina A potent and selective endogenous agonist for the μ-opiate receptor. Nature 1997 PMID: 9087409
- Harrison Differential effects of endomorphin-1, endomorphin-2, and tyr-W-MIF-1 on activation of G-proteins in SH-SY5Y human neuroblastoma membranes. Peptides 1998 PMID: 9622031
- Kakizawa Parallel stimulations of in vitro and in situ [35S]GTPγS binding by endomorphin 1 and DAMGO in mouse brains. Peptides 1998 PMID: 9622032
- Goldberg Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J.Pharmacol.Exp.Ther. 1998 PMID: 9694962
Product Specific Notices for Endomorphin-1
For research use only
Loading...
Loading...