DREADD agonist 21 dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 6422
Potent hM3Dq and hM4Di DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
Key Product Details
Description
Potent hM3Dq and hM4Di DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
Alternative Names
Compound 21 (water-soluble)
Product Description
DREADD agonist 21 dihydrochloride is a water soluble version of DREADD agonist 21 (Cat. No. 5548). Potent muscarinic DREADD agonist.Product Specifications
Molecular Weight
351.27
Formula
C17H18N4.2HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride
CAS Number
2250025-92-2
PubChem ID
134812837
InChI Key
SETCOPAXYQJWKI-UHFFFAOYSA-N
SMILES
C1(N2CCNCC2)=NC(C=CC=C3)=C3NC4=C1C=CC=C4.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 35.13 | 100 | |
| DMSO | 35.13 | 100 |
Preparing Stock Solutions
for DREADD agonist 21 dihydrochloride
The following data is based on the product molecular weight 351.27
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.85 mL | 14.23 mL | 28.47 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
| 10 mM | 0.28 mL | 1.42 mL | 2.85 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.57 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chen The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem.Neurosci. 2015 PMID: 25587888
Product Specific Notices for DREADD agonist 21 dihydrochloride
For research use only
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