(±)-Eriodictyol

Tocris Bioscience, part of Bio-Techne | Catalog # 7199

Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling
Discontinued Product
7199 has been discontinued. View all TRPV Inhibitors products.

Key Product Details

Description

Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling

View all TRPV Inhibitors »

Product Description

(±)-Eriodictyol is a potent TRPV1 antagonist. Inhibits capsaicin (Cat. No. 0462) -induced Ca2+ influx in synaptosomes. Exhibits antinociceptive activity in animal models without affecting body temperature. Also antioxidant; protects against H2O2-induced neurotoxicity in vitro by activation of Nrf2/ARE signaling. Modeling studies predict binding to ACE2 preventing its interaction with SARS-CoV-2 S protein. Naturally-derived flavonoid. Orally bioavailable.

Product Specifications

Molecular Weight

288.26

Formula

C15H12O6

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one

CAS Number

4049-38-1

PubChem ID

11095

InChI Key

SBHXYTNGIZCORC-UHFFFAOYSA-N

SMILES

OC1=CC(O)=C2C(CC(C3=CC(O)=C(C=C3)O)OC2=C1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.83 100
Ethanol 14.41 50

Preparing Stock Solutions for (±)-Eriodictyol

The following data is based on the product molecular weight 288.26

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.47 mL 17.35 mL 34.69 mL
5 mM 0.69 mL 3.47 mL 6.94 mL
10 mM 0.35 mL 1.73 mL 3.47 mL
50 mM 0.07 mL 0.35 mL 0.69 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (±)-Eriodictyol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (±)-Eriodictyol

For research use only

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