Combretastatin A4

Name: Combretastatin A4
Brand: Tocris Bioscience
SKU: 1495

Tocris Bioscience, part of Bio-Techne | Catalog # 1495

Citations (9)

COA / SDS

Antiangiogenic

Discontinued Product

1495 has been discontinued. View all Microtubule Binding Compounds products.

Key Product Details

Description:	Antiangiogenic
Alternative Names:	CRC 87-09,NSC 817373
Chemical Name:	2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
Purity:	≥99%
Molecular Weight:	316.35

View Full Technical Details for Combretastatin A4

Technical Data
Citations

Biological Activity for Combretastatin A4

Antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Inhibits tubulin polymerization.

Technical Data for Combretastatin A4

M. Wt	316.35
Formula	C₁₈H₂₀O₅
Storage	Desiccate at -20°C
Purity	≥99%
CAS Number	117048-59-6
PubChem ID	5351344
InChi Key	HVXBOLULGPECHP-WAYWQWQTSA-N
Smiles	OC1=CC(\C=C/C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Combretastatin A4

References are publications that support the biological activity of the product.

Griggs Potent anti-metastatic activity of combretastatin-A4. Int.J.Oncol. 2001 PMID: 11562761
Lin Combretastatin A4-induced differential cytotoxicity and reduced metastatic ability by inhibition of AKT function in human gastric cancer cells. J.Pharmacol.Exp.Ther. 2007 PMID: 17646428
Dorr Antitumor activity of combretastatin-A4 phosphate, a natural product tubulin inhibitor. Invest.New Drugs 1996 PMID: 8913833

Combretastatin A4

Tocris Bioscience, part of Bio-Techne | Catalog # 1495

Key Product Details

Biological Activity for Combretastatin A4

Technical Data for Combretastatin A4

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Combretastatin A4

Product Documents for Combretastatin A4

COA

Certificate of Analysis

SDS

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