CL 075

Tocris Bioscience, part of Bio-Techne | Catalog # 6142

TLR8 agonist
Discontinued Product
6142 has been discontinued. View all Toll-like Receptor Agonists products.

Key Product Details

Description

TLR8 agonist

View all Toll-like Receptor Agonists »

Product Description

CL 075 is a TLR8 agonist. Induces production of TNF-α and IL-12 from peripheral blood mononuclear cells (PBMCs). Promotes maturation of monocyte-derived dendritic cells in combination with Poly(I:C) (Cat. No. 4287).

Product Specifications

Molecular Weight

243.33

Formula

C13H13N3S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-Propylthiazolo[4,5-c]quinolin-4-amine

CAS Number

256922-53-9

PubChem ID

10198719

InChI Key

NFYMGJSUKCDVJR-UHFFFAOYSA-N

SMILES

CCCC1=NC2=C(N=C3C=CC=CC3=C2S1)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 12.17 50
Ethanol 2.43 10

Preparing Stock Solutions for CL 075

The following data is based on the product molecular weight 243.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 8.22 mL 41.10 mL 82.19 mL
2.5 mM 1.64 mL 8.22 mL 16.44 mL
5 mM 0.82 mL 4.11 mL 8.22 mL
25 mM 0.16 mL 0.82 mL 1.64 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for CL 075

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CL 075

For research use only

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