BromoTag® cis-AGB1
Tocris Bioscience, part of Bio-Techne | Catalog # 7687
Negative control for BromoTag® AGB1 (Cat. No. 7686)
Key Product Details
Description
Negative control for BromoTag® AGB1 (Cat. No. 7686)
Product Description
BromoTag® cis-AGB1 is a negative control for BromoTag AGB1 (Cat. No. 7686). Exhibits no significant VHL binding affinity.BromoTag® is a registered trademark of the University of Dundee and is used under license
Licensing Information
Sold under exclusive licence from the University of DundeeProduct Specifications
Molecular Weight
1031.68
Formula
C51H63ClN8O9S2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(S)-13-((2S,4S)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecyl (R)-2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoate
CAS Number
2776190-80-6
InChI Key
ILEZCIMECSOYKF-HENOJDTBSA-N
SMILES
ClC1=CC=C(C2=N[C@@H]([C@H](C(OCCOCCOCCOCC(N[C@H](C(N3C[C@H](C[C@H]3C(NCC4=CC=C(C5=C(N=CS5)C)C=C4)=O)O)=O)C(C)(C)C)=O)=O)CC)C6=NN=C(C)N6C7=C2C(C)=C(S7)C)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 103.17 | 100 |
Preparing Stock Solutions
for BromoTag® cis-AGB1
The following data is based on the product molecular weight 1031.68
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.97 mL | 4.85 mL | 9.69 mL |
| 5 mM | 0.19 mL | 0.97 mL | 1.94 mL |
| 10 mM | 0.10 mL | 0.48 mL | 0.97 mL |
| 50 mM | 0.02 mL | 0.10 mL | 0.19 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bond Development of BromoTag: a "Bump-and-Hole"-PROTAC system to induce potent, rapid, and selective degradation of tagged target proteins. J.Med.Chem. 2021 PMID: 34652918
Product Specific Notices for BromoTag® cis-AGB1
For research use only
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