Bifemelane hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0767
Non-selective MAO inhibitor
Discontinued Product
0767 has been discontinued.
View all Monoamine Oxidase (MAO) Inhibitors products.
Key Product Details
Description
Non-selective MAO inhibitor
Product Description
Bifemelane hydrochloride is an antidepressant MAO inhibitor. Reverses catalepsy induced by Tetrabenazine (Cat. No. 2175) in mice and increases locomotor activity in MPTP-treated marmosets.Product Specifications
Molecular Weight
305.84
Formula
C18H23NO.HCl
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride
CAS Number
62232-46-6
PubChem ID
43962
InChI Key
MEAHDXWXNNDSAK-UHFFFAOYSA-N
SMILES
Cl.CNCCCCOC1=CC=CC=C1CC1=CC=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 30.58 | 100 | |
| DMSO | 30.58 | 100 |
Preparing Stock Solutions
for Bifemelane hydrochloride
The following data is based on the product molecular weight 305.84
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.27 mL | 16.35 mL | 32.70 mL |
| 5 mM | 0.65 mL | 3.27 mL | 6.54 mL |
| 10 mM | 0.33 mL | 1.63 mL | 3.27 mL |
| 50 mM | 0.07 mL | 0.33 mL | 0.65 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Nomoto Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 1994 PMID: 7816348
- Tobe Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneimittelforschung 1981 PMID: 7197535
- Naoi 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 1988 PMID: 3335842
Product Specific Notices for Bifemelane hydrochloride
For research use only
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