Bax inhibitor peptide V5
Tocris Bioscience, part of Bio-Techne | Catalog # 1785
Inhibitor of Bax-mediated apoptosis
Discontinued Product
1785 has been discontinued.
View all Bcl-2 Family Inhibitors products.
Key Product Details
Description
Inhibitor of Bax-mediated apoptosis
Product Description
Bax inhibitor peptide V5 is a cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro.Control Peptide also available.
Licensing Information
Sold under licenseProduct Specifications
Molecular Weight
586.79
Formula
C27H50N6O6S
Storage
Desiccate at -20°C
CAS Number
579492-81-2
PubChem ID
10129115
InChI Key
NHMUTADCTDDWPV-YFNVTMOMSA-N
SMILES
[H]N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Yoshida Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 2004 PMID: 15358121
- Sawatzky The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 2006 PMID: 16400007
Product Specific Notices for Bax inhibitor peptide V5
For research use only
Loading...
Loading...