Adenosine 5'-(α,β-methylene)diphosphate sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 3633

Ecto-5'-nucleotidase (CD73) inhibitor
Discontinued Product
3633 has been discontinued. An alternative/replacement product is available: 8173. View all NTPDase Inhibitors products.

Key Product Details

Description

Ecto-5'-nucleotidase (CD73) inhibitor

Alternative Names

AMPCP,APCP

View all NTPDase Inhibitors »

Product Description

Adenosine 5'-(α,β-methylene)diphosphate sodium salt is an ecto-5'-nucleotidase/CD73 inhibitor. Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells (MCF7/A6 and L1210/A). Also increases rhodamine uptake and inhibits rhodamine efflux from ecto-5'-nucleotidase-positive MDR cells. Vasoconstrictor.

Product Specifications

Molecular Weight

447.21

Formula

C11H16N5NaO9P2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

α,β-Methyleneadenosine 5'-diphosphate monosodium salt

CAS Number

89016-30-8

PubChem ID

91691113

InChI Key

RFGZKSPLJPHQMI-RDJRRFHDSA-M

SMILES

NC1=C2C(N([C@@H]3O[C@H](COP(CP(O)(O[Na])=O)(O)=O)[C@@H](O)[C@@H]3O)C=N2)=NC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in water (supplied pre-dissolved at a concentration of 10mM)

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Adenosine 5'-(α,β-methylene)diphosphate sodium salt

For research use only

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