Abn-CBD

Name: Abn-CBD
Brand: Tocris Bioscience
SKU: 1297

Tocris Bioscience, part of Bio-Techne | Catalog # 1297

Citations (9)

COA / SDS

Selective GPR55 agonist; neurobehaviorally inactive

Discontinued Product

1297 has been discontinued. View all GPR55 Receptor Agonists products.

Key Product Details

Description:	Selective GPR55 agonist; neurobehaviorally inactive
Alternative Names:	Abnormal-cannabidiol
Chemical Name:	4-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
Purity:	≥97% (HPLC)
Molecular Weight:	314.47

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Technical Data
Citations

Biological Activity for Abn-CBD

Abn-CBD is a neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 (EC₅₀ values are 2.5, >30 and >30 μM at GPR55, CB₁ and CB₂ receptors respectively). Increases phosphorylation of protein kinases in, and migration of, human umbilical vein endothelial cells.

Technical Data for Abn-CBD

M. Wt	314.47
Formula	C₂₁H₃₀O₂
Storage	Desiccate at -20°C
Purity	≥97% (HPLC)
CAS Number	22972-55-0
PubChem ID	89949
InChi Key	YWEZXUNAYVCODW-RBUKOAKNSA-N
Smiles	C=[C@](C)[C@@H]1CCC(C)=C[C@H]1[C@]2=C(O)C=C(O)C=C2CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Abn-CBD

References are publications that support the biological activity of the product.

Ryberg The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 2007 PMID: 17876302
Jarai Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc.Natl.Acad.Sci.U.S.A. 1999 PMID: 10570211
Mo Atypical cannabinoid stimulates endothelial cell migration via a G_i/G_o-coupled receptor distinct from CB₁, CB₂ or EDG-1. Eur.J.Pharmacol. 2004 PMID: 15063151
Ho and Hiley Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery. Br.J.Pharmacol. 2003 PMID: 12711633

Abn-CBD

Tocris Bioscience, part of Bio-Techne | Catalog # 1297

Key Product Details

Biological Activity for Abn-CBD

Technical Data for Abn-CBD

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Abn-CBD

Product Documents for Abn-CBD

COA

Certificate of Analysis

SDS

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