6-Bnz-cAMP sodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 5255
Cell permeable cAMP analog
Product Description
6-Bnz-cAMP sodium salt is a cell permeable cAMP analog; selectively activates cAMP-dependent PKA but not Epac signaling pathways. Acts synergistically with 8-CPT-2Me-cAMP (Cat. No. 1645) to inhibit vascular smooth muscle cell proliferation.Product Specifications
Molecular Weight
455.29
Formula
C17H15N5NaO7P
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-Benzoyladenosine cyclic 3',5'-(hydrogen phosphate) monosodium salt
CAS Number
1135306-29-4
PubChem ID
23672707
InChI Key
SPYGSKQRPXISIB-FKVBDRBCSA-M
SMILES
[H][C@@]([C@@](O[C@@H](N3C=NC4=C3N=CN=C4NC(C5=CC=CC=C5)=O)[C@@H]2O)([H])CO1)2OP1(O[Na])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 45.53 | 100 |
Preparing Stock Solutions
for 6-Bnz-cAMP sodium salt
The following data is based on the product molecular weight 455.29
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.20 mL | 10.98 mL | 21.96 mL |
| 5 mM | 0.44 mL | 2.20 mL | 4.39 mL |
| 10 mM | 0.22 mL | 1.10 mL | 2.20 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.44 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hewer PKA and Epac synergistically inhibit smooth muscle cell proliferation. J.Mol.Cell Cardiol. 2011 PMID: 20971121
Product Specific Notices for 6-Bnz-cAMP sodium salt
For research use only
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