INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human SP-D concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
Surfactant Protein D (SP-D) is a collectin family protein consisting of a collagen-like sequence followed by a C-type lectin domain. It is synthesized primarily in the lung by alveolar type II cells and unciliated bronchial epithelial cells. In addition, SP-D is produced by epithelial cells of the gastrointestinal tract and exocrine glands. SP-D binds to patterns of neutral sugars on micro-organisms to mediate direct opsonization and phagocytosis and is an important component of the innate immune system.
Product Specifications for Simple Plex Control for Human SP-D
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Source
N/A
Preparation & Storage
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt. • Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended. • Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: SP-D
Item
Value
Long Name
Surfactant Pulmonary Associated Protein D
Entrez Gene IDs
6441 (Human); 20390 (Mouse)
Alternate Names
COLEC7collectin-7, Collectin 7, Collectin-7, Lung surfactant protein D, PSP-D, PSPD, SFTP4, SFTP4pulmonary surfactant-associated protein D, SFTPD, SP-D, SP-Dpulmonary surfactant apoprotein, SPD, surfactant protein D, surfactant, pulmonary-associated protein D, surfactant-associated protein, pulmonary 4
