PML Protein Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NB100-59787PEP

Novus Biologicals, part of Bio-Techne
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NB100-59787PEP
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all PML Proteins and Enzymes »

Product Specifications

Description

Application Notes

This peptide is useful as a blocking peptide for NB100-59787. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB100-59787 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB100-59787PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: PML

PML Protein is encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.

Long Name

Promyelocytic Leukemia

Alternate Names

MYL, RNF71, TRIM19

Gene Symbol

PML

Additional PML Products

Product Documents for PML Protein Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PML Protein Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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