Recombinant Human DUSP26 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23009

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NBP2-23009
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all DUSP26 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-211 of Human DUSP26

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

26.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human DUSP26 His Protein

SDS-PAGE: Recombinant Human DUSP26 His Protein [NBP2-23009]

SDS-PAGE: Recombinant Human DUSP26 His Protein [NBP2-23009]

SDS-Page: DUSP26 Protein [NBP2-23009]

Formulation, Preparation and Storage

NBP2-23009
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 0.4M UREA
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DUSP26

DUSP26 inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. This protein inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. DUSP26 can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Recombinant human DUSP26 protein, fused to His-tag at N-terminus, was expressed in E.coli .

Alternate Names

DSP-4, dual specificity phosphatase 26 (putative), Dual specificity phosphatase SKRP3, dual specificity protein phosphatase 26, dual-specificity phosphatase SKRP3, DUSP24SKRP3, EC 3.1.3.16, EC 3.1.3.48, LDP4, LDP-4, Low-molecular-mass dual-specificity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen-activated protein kinase phosphatase 8, MKP8, MKP-8, NATA1, Novel amplified gene in thyroid anaplastic cancer

Gene Symbol

DUSP26

Additional DUSP26 Products

Product Documents for Recombinant Human DUSP26 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human DUSP26 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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