ARHGEF6 Recombinant Protein Antigen

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25284PEP

Novus Biologicals, part of Bio-Techne
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NBP3-25284PEP
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Key Product Details

Conjugate

Unconjugated

Applications

Antibody Competition

View all ARHGEF6 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human ARHGEF6

Source: E.coli

Amino Acid Sequence: GSVEKFCLDPQTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQR

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

Purity

>80% by SDS-PAGE and Coomassie blue staining

Applications

Antibody Competition (10-100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-25284It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com.

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation and Storage

NBP3-25284PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: ARHGEF6

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq]

Alternate Names

alphaPIX, Alpha-Pix, COOL-2, COOL2alpha, KIAA0006Cool2, mental retardation, X-linked 46, MRX46, PAK-interacting exchange factor alpha, PIXA, Rac/Cdc42 guanine exchange factor (GEF) 6, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6, Rac/Cdc42 guanine nucleotide exchange factor 6, rho guanine nucleotide exchange factor 6

Gene Symbol

ARHGEF6

Additional ARHGEF6 Products

Product Documents for ARHGEF6 Recombinant Protein Antigen

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ARHGEF6 Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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