Normal Human IgG Control
Catalog # 1-001-A | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Summary for Normal Human IgG Control
Immunogen
Clonality
Host
Isotype
Applications for Normal Human IgG Control
Control
Reviewed Applications
Read 5 reviews rated 4.8 using 1-001-A in the following applications:
Published Applications
Read 37 publications using 1-001-A in the following applications:
- Bioassay (1 Publication)
- Blocking (1 Publication)
- Control (9 Publications)
- ELISA Standard (1 Publication)
- Fc Blocking (1 Publication)
- Flow Cytometry (1 Publication)
- Functional Assay (2 Publications)
- ICC (1 Publication)
- IHC (1 Publication)
- Immunoprecipitation (1 Publication)
- In Vivo (3 Publications)
- In Vivo Control (1 Publication)
- Isotype Control (6 Publications)
- Migration Assay Control (1 Publication)
- Neutralization (4 Publications)
- Neutralization Control (1 Publication)
- Western Blot (1 Publication)
Formulation, Preparation and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
♦ 6 months from date of receipt at 2 to 8 °C
Background: IgG
R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.
Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.
Long Name
Alternate Names
Product Documents for Normal Human IgG Control
Product Specific Notices for Normal Human IgG Control
Contains sodium azide. Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
For research use only
Citations for Normal Human IgG Control (37)
Citations are publications that use Bio-Techne products. Selected citations for Normal Human IgG Control include:
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Species: Mouse
Sample Types: In Vivo
Applications: In VivoMA Erickson et al. (2023-01-20), Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 Variants of Concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease Brain, Behavior, and Immunity, 2023-00(0).
PMID: 36682515 -
Species: Human
Sample Types: Whole Cells
Applications: Migration Assay ControlS Okikawa et al. (2022-02-16), Inhibition of the VEGF signaling pathway attenuates tumor?associated macrophage activity in liver cancer Oncology reports, 2022-047(4).
PMID: 35169858 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo ControlD Scheggia et al. (2021-07-09), GluA3 autoantibodies induce alterations in dendritic spine and behavior in mice Brain, Behavior, and Immunity, 2021-00(0).
PMID: 34246733 -
Species: Human
Sample Types: Whole Cells
Applications: Neutralization ControlYF Sun et al. (2021-07-02), Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma Nature Communications, 2021-012(1):4091.
PMID: 34215748 -
Species: Human
Sample Types: Whole Cells
Applications: ICCAM Eid et al. (2021-03-09), Synthesis and Biological Evaluation of Novel Isoxazole-Amide Analogues as Anticancer and Antioxidant Agents BioMed Research International, 2021-02021(0):6633297.
PMID: 33763478 -
Species: Human
Sample Types: Whole Cells
Applications: Isotype ControlJW Oh et al. (2021-01-20), High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted Glioblastoma Cancers, 2021-013(3).
PMID: 33498427 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Wada et al. (2020-12-08), The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment Oncotarget, 2020-111(49):4593-4604.
PMID: 33346211 -
Species: Mouse
Sample Types: Reference Standard
Applications: ControlA Usui-Ouchi et al. (2020-10-26), An allosteric peptide inhibitor of HIF-1&alpha regulates hypoxia-induced retinal neovascularization Proc Natl Acad Sci U S A, 2020-10(0).
PMID: 33106407 -
Species: Human
Sample Types: Whole Cells
Applications: Isotype ControlN Thornton et al. (2020-07-16), Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype Nat Commun, 2020-011(1):3569.
PMID: 32678083 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoP Korangath et al. (2020-03-25), Nanoparticle interactions with immune cells dominate tumor retention and induce T cell-mediated tumor suppression in models of breast cancer Sci Adv, 2020-06(13):eaay1601.
PMID: 32232146 -
Species: Human
Sample Types: Protein
Applications: ELISA StandardGM Bwire et al. (2019-04-27), Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin BMC Immunol., 2019-020(1):12.
PMID: 31029083 -
Species: Human
Sample Types: Whole Cells
Applications: Isotype ControlP Guo et al. (2019-04-17), ITGA2 as a potential nanotherapeutic target for glioblastoma Sci Rep, 2019-09(1):6195.
PMID: 30996239 -
Species: Human
Sample Types: Tissue Homogenates
Applications: ImmunoprecipitationHH Chen et al. (2018-11-13), Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression Sci Rep, 2018-18(1):16725.
PMID: 30425303 -
Species: Human
Sample Types: Whole Cells
S Merfeld-Cl et al. (2017-08-18), Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity J. Cell. Mol. Med., 2017-00(0).
PMID: 28834227 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationS Mujib et al. (2017-07-27), Comprehensive cross-clade characterization of antibody-mediated recognition, complement-mediated lysis and cell-mediated cytotoxicity of HIV-1 envelope specific antibodies towards the eradication of the HIV-1 reservoir J. Virol., 2017-00(0).
PMID: 28592534 -
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay(2016-07-07), HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses Sci Rep, 2016-06(0):29447.
PMID: 27385120 -
Species: Mouse
Sample Types: Cell Lysates
Applications: ControlYoko Ono et al. (2016-03-18), Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase. Scientific Reports, 2016-00(0):2045-2322.
PMID: 26988030 -
Species: Bacteria - E. Coli
Sample Types: Virus
Applications: Isotype ControlYang L et al. (2015-06-02), Active immunization with Tocilizumab mimotopes induces specific immune responses. BMC Biotechnol, 2015-015(0):46.
PMID: 26033236 -
Species: Human
Sample Types: Whole Cells
Applications: Isotype ControlCaiazza F et al. (2015-05-26), Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple-negative breast cancer cells. Br J Cancer, 2015-0112(12):1895-903.
PMID: 26010411 -
Species: Mouse
Sample Types: Whole Organism
Applications: ControlBai Y et al. (2015-04-17), Pericytes contribute to the disruption of the cerebral endothelial barrier via increasing VEGF expression: implications for stroke. PLoS ONE, 2015-010(4):e0124362.
PMID: 25884837 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationPahlman L et al. (2015-03-07), Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-beta1. BMC Pulm Med, 2015-015(0):19.
PMID: 25851169 -
Species: Human
Sample Types: Whole Cells
Applications: ControlKuang D et al. (2014-09-17), B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest, 2014-0124(10):4657-67.
PMID: 25244097 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoBeverley P et al. (2014-07-28), A novel murine cytomegalovirus vaccine vector protects against Mycobacterium tuberculosis. J Immunol, 2014-0193(5):2306-16.
PMID: 25070842 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationJajosky A et al. (2014-05-22), RepSox slows decay of CD34+ acute myeloid leukemia cells and decreases T cell immunoglobulin mucin-3 expression. Stem Cells Transl Med, 2014-03(7):836-48.
PMID: 24855276 -
Species: Human
Sample Types: Whole Cells
Applications: Functional AssayDuluc D et al. (2014-05-16), Induction and activation of human Th17 by targeting antigens to dendritic cells via dectin-1. J Immunol, 2014-0192(12):5776-88.
PMID: 24835401 -
Species: Human
Sample Types: Whole Cells
Applications: Isotype ControlAlizadeh H et al. (2014-03-14), Pathogenic strains of Acanthamoeba are recognized by TLR4 and initiated inflammatory responses in the cornea. PLoS ONE, 2014-09(3):e92375.
PMID: 24633052 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationPrigent L et al. (2014-02-18), The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation. Eur J Immunol, 2014-044(5):1330-40.
PMID: 24549985 -
Species: Human
Sample Types: Whole Cells
Applications: ControlMacas J et al. (2014-01-01), Generation of neuronal progenitor cells in response to tumors in the human brain. Stem Cells, 2014-032(1):244-57.
PMID: 24170295 -
Species: Human
Sample Types: Protein,Whole Cells
Applications: IHC,Western BlotKryza T et al. (2013-11-13), Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway. FASEB J, 2013-128(2):740-51.
PMID: 24225148 -
Species: Human
Sample Types: Whole Cells
Applications: ControlRichards FM et al. (2012-07-11), Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo. PLoS ONE, 2012-07(7):e40597.
PMID: 22792380 -
Species: Human
Sample Types: Whole Cells
Applications: BlockingWilhelmsen K et al. (2012-06-15), ERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytes. J Biol Chem, 2012-0287(32):26478-94.
PMID: 22707717 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometrySisto M et al. (2012-04-19), Sjogren's syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-kappaB. Genes Immun., 2012-013(5):411-20.
PMID: 22513453 -
Species: Hamster,Human
Sample Types: Whole Cells
Applications: Fc BlockingNoyce RS et al. (2011-08-25), Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus. PLoS Pathog., 2011-07(8):e1002240.
PMID: 21901103 -
Species: Human
Sample Types: RNA
Applications: ControlLi N et al. (2011-06-08), Inhibition of Cell Proliferation by an Anti-EGFR Aptamer. PLoS ONE, 2011-06(6):e20299.
PMID: 21687663 -
Species: Human
Sample Types: Whole Cells
Applications: ControlGijsen M et al. (2010-12-21), HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer. PLoS Biol., 2010-18(12):e1000563.
PMID: 21203579 -
Species: Human
Sample Types: Whole Cells
Kalliolias GD et al. (2010-10-22), Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27. J. Immunol., 2010-1185(11):7047-56.
PMID: 20971923 -
Species: Mouse
Sample Types: In Vivo
Applications: ControlYamamoto M et al. (2008-12-01), TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche. Cancer Res., 2008-168(23):9754-62.
PMID: 19047154
There are no citations that match your criteria.
Customer Reviews for Normal Human IgG Control (5)
Customer Images
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Application: Western BlotSample Tested: 293T human embryonic kidney cell lineSpecies: HumanVerified Customer | Posted 02/16/2020IgG was used as negative control.
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Application: Functional AssaySample Tested: Bladder cancer tissueSpecies: HumanVerified Customer | Posted 02/04/2020UM-UC3 bladder cancer cells were transiently transfected with a Notch-reporter Firefly luciferase plasmid, in addition to an internal Renilla control. IgG was used as a negative stimulation control, whereas Jagged 1 was used to induce a Notch-specific response. Increasing concentrations of the Gamma-secretase inhibitor DAPT resulted in a dose-dependent decrease in Notch signal.
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Application: Western BlotSample Tested: Recombinant proteinSpecies: HumanVerified Customer | Posted 09/22/2019
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Application: Flow CytometrySample Tested: MBA-MB-123 human breast cancer cell lineSpecies: HumanVerified Customer | Posted 10/27/2018Used at 10 ug/mL works perfectly as a human Isotype control for flow cytometry. There is no background binding in live cells that do not express Fc receptor. The attached image shows MFI with and without the isotype control indicating identical signal.
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Application: Flow CytometrySample Tested: Human annulus pulposus cell cultureSpecies: HumanVerified Customer | Posted 01/27/2015
There are no reviews that match your criteria.
FAQs for Normal Human IgG Control
Reconstitution Calculator
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