3-Cyano-7-ethoxycoumarin

Name: 3-Cyano-7-ethoxycoumarin
Brand: Tocris Bioscience
SKU: 4815

Tocris Bioscience, part of Bio-Techne | Catalog # 4815

COA / SDS

Fluorescent cytochrome P450 substrate

Discontinued Product

4815 has been discontinued. View all Enzyme Probes and Enzyme Substrates products.

Key Product Details

Description:	Fluorescent cytochrome P450 substrate
Chemical Name:	7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
Purity:	≥98% (HPLC)
Molecular Weight:	215.2

View Full Technical Details for 3-Cyano-7-ethoxycoumarin

Technical Data
Citations

Biological Activity for 3-Cyano-7-ethoxycoumarin

3-Cyano-7-ethoxycoumarin is a fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.

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Technical Data for 3-Cyano-7-ethoxycoumarin

M. Wt	215.2
Formula	C₁₂H₉NO₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	117620-77-6
PubChem ID	164045
InChi Key	YAFGHMIAFYQSCF-UHFFFAOYSA-N
Smiles	O=C2C(C#N)=CC1=CC=C(OCC)C=C1O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 3-Cyano-7-ethoxycoumarin

References are publications that support the biological activity of the product.

Donato Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab.Dispos. 2004 PMID: 15205384
White A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal.Biochem. 1988 PMID: 3189781