QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1

Name: QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1
Brand: R&D Systems
SKU: QC325

R&D Systems, part of Bio-Techne | Catalog # QC325

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Product Datasheet / COA / SDS

Control Set 1246

Key Product Details

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Technical Data
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Product Specifications for QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1

Measurement	Quantitative ELISA
Reactivity	Human, Cynomolgus Monkey

Preparation and Storage

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: PD-L1/B7-H1

PD-L1, also known as B7-H1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 is expressed on inflammatory-activated immune cells including macrophages, T cells, and B cells, keratinocytes, enothelial and intestinal epithelial cells, as well as a variety of carcinomas and melanoma. PD-L1 binds to T cell B7-1/CD80 and PD-1. It suppresses T cell activation and proliferation and induces the apoptosis of activated T cells. It plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development. PD-L1 favors the development of anti-inflammatory IL-10 and IL-22 producing dendritic cells and inhibits the development of Th17 cells. In cancer, PD-L1 provides resistance to T cell mediated lysis, enhances EMT, and enhances the tumorigenic function of Th22 cells.

Item	Value
Long Name	Programmed Death Ligand 1
Entrez Gene IDs	29126 (Human); 60533 (Mouse); 499342 (Rat); 574058 (Porcine); 484186 (Canine); 102145573 (Cynomolgus Monkey)
Alternate Names	Avelumab, B7-H, B7-H1, B7H1, B7H1PDCD1L1, CD274, CD274 antigenMGC142294, CD274 molecule, PD-L1, PD-L1B7 homolog 1, PDCD1L1, PDCD1LG1, PDCD1LG1MGC142296, PDL1, PDL1PDCD1 ligand 1, Programmed death ligand 1, programmed cell death 1 ligand 1

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QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1

R&D Systems, part of Bio-Techne | Catalog # QC325

Key Product Details

View all PD-L1/B7-H1 ELISA Kits »

Product Specifications for QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1

Preparation and Storage

Background: PD-L1/B7-H1

Customer Reviews for QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1

Product Documents for QuicKit Control for Human/Cynomolgus Monkey PD-L1/B7-H1

Product Datasheets

COA

Certificate of Analysis

SDS

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