Human SMC1 (NP_006297) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1533
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: SMC1
The ATM protein kinase phosphorylates SMC1 protein in cells exposed to genotoxins. Overexpression of a non-phosphorylatable mutant of SMC1 subjects a cell to a defective S phase checkpoint and decreased cell survival in response to genotoxic stress. In cells expressing this mutant, BRCA1 and Nbs1 are still phosphorylated, suggesting that SMC1 phosphorylation is downstream of these other phosphorylation events.
Long Name
Structural Maintenance of Chromosomes 1
Alternate Names
SB1.8, SMC1A, SMC1L1
Gene Symbol
SMC1A
UniProt
Additional SMC1 Products
Product Documents for Human SMC1 (NP_006297) VersaClone cDNA
Product Specific Notices for Human SMC1 (NP_006297) VersaClone cDNA
For research use only
Loading...
Loading...
Loading...