Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1081
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: LILRA4/CD85g/ILT7
LILRA4, also known as ILT7 and CD85g, is a transmembrane immunoregulatory protein that is expressed on plasmacytoid dendritic cells (pDC) but is downregulated in response to TLR9 signaling. It associates with Fc epsilon RI gamma, and this complex binds to cell surface BST2/Tetherin on monocytes, plasmacytoid and myeloid dendritic cells, B cells, and activated CD4+ and CD8+ T cells. This interaction inhibits the TLR7 and TLR9 induced pDC production of type I interferons, IL-6, and TNF-alpha.
Long Name
Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 4
Alternate Names
CD85g, ILT7
Entrez Gene IDs
23547 (Human)
Gene Symbol
LILRA4
UniProt
Additional LILRA4/CD85g/ILT7 Products
Product Documents for Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
Product Specific Notices for Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
For research use only
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