Human IL-18 R beta/IL-1 R7 (NP_003844) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1118
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-18 R beta/IL-1 R7
The functional IL-18 receptor complex is composed of two subunits designated IL-18 R alpha (also termed IL-1 R5 and IL-1 Rrp) and IL-18 R beta (also termed IL-1 R7 and AcPL). Both IL-18 R alpha and IL-18 R beta belong to the IL-1 receptor family. Although IL-18 R alpha by itself binds IL-18 with low-affinity and IL-18 R beta does not bind IL-18 in vitro, co-expression of IL-18 R alpha and IL-18 R beta is required for high-affinity binding and IL-18 responsiveness. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta. It is not expressed in brain, skeletal muscle, kidney and pancreas.
Long Name
Interleukin 18 Receptor beta
Alternate Names
AcPL, CD218b, IL-1 R7, IL-18Rb, IL18R beta, IL18RAP
Gene Symbol
IL18RAP
UniProt
Additional IL-18 R beta/IL-1 R7 Products
Product Documents for Human IL-18 R beta/IL-1 R7 (NP_003844) VersaClone cDNA
Product Specific Notices for Human IL-18 R beta/IL-1 R7 (NP_003844) VersaClone cDNA
For research use only
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