Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1361
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IFN-alpha/beta R2
IFN-alpha/beta R2, also known as IFNAR2, is a 100 kDa component of the class II cytokine receptor that binds the type I interferons IFN-alpha, IFN-beta, and IFN-omega. IFN-alpha/beta R2 associates with the 125 kDa IFN-alpha/beta R1 component to form a receptor complex that transmits antiviral and antiproliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation. A soluble form of the protein, corresponding to the extracellular ligand-binding domain, is generated by alternative splicing.
Long Name
Interferon alpha/beta Receptor 2
Alternate Names
IFN-aR2, IFN-bR2, IFNAR2, IFNbR2
Gene Symbol
IFNAR2
UniProt
Additional IFN-alpha/beta R2 Products
Product Documents for Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA
Product Specific Notices for Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA
For research use only
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