Human FYB/ADAP/SLAP130 (NP_955367) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1173
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: FYB/ADAP/SLAP130
FYB, also known as ADAP and SLAP130, is a 130 kDa hematopoietic-specific adaptor protein which contains an SH3-VASP homology 1 domain. It associates with other cytoplasmic proteins such as SH2-containing Leukocyte Phosphoprotein of 76 kDa (SLP-76). SLAP130 is phosphorylated in response to TCR/CD3 stimulation, and regulates the stability of SKAP55. A SLAP130:SKAP55 signaling module stimulates beta 1 and beta 2 integrin activation and promotes T cell-DC cell interaction.
Long Name
FYN Binding Protein (FYB-120/130)
Alternate Names
ADAP, PRO0823, SLAP130
Gene Symbol
FYB1
UniProt
Additional FYB/ADAP/SLAP130 Products
Product Documents for Human FYB/ADAP/SLAP130 (NP_955367) VersaClone cDNA
Product Specific Notices for Human FYB/ADAP/SLAP130 (NP_955367) VersaClone cDNA
For research use only
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