ZNRF3 Antibody (2035A) [Janelia Fluor® 669]
Novus Biologicals, part of Bio-Techne | Catalog # FAB8328JF669
Recombinant Monoclonal Antibody.
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunocytochemistry
Label
Janelia Fluor 669
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 2035A
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse ZNRF3
Lys53-Met216
Accession # Q5SSZ7
Lys53-Met216
Accession # Q5SSZ7
Specificity
Detects mouse ZNRF3 in direct ELISAs.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Applications for ZNRF3 Antibody (2035A) [Janelia Fluor® 669]
Application
Recommended Usage
Immunocytochemistry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from cell culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: ZNRF3
The cell-surface transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) and its homologue ring finger 43 (RNF43) are negative feedback regulators of Wnt signaling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signaling by promoting the turnover of frizzled and LRP6. R-spondin may enhance Wnt signaling by inhibiting ZNRF3. ZNRF3 may be a target for therapeutic exploration.
Long Name
Zinc and Ring Finger 3
Alternate Names
BK747E2.3, KIAA1133, RNF203
Additional ZNRF3 Products
Product Documents for ZNRF3 Antibody (2035A) [Janelia Fluor® 669]
Product Specific Notices for ZNRF3 Antibody (2035A) [Janelia Fluor® 669]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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