ZCCHC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85135

Novus Biologicals, part of Bio-Techne
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NBP1-85135-25ul
NBP1-85135
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ZCCHC8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids:PGWLKEAELENSGLALYDGKDGTDGETEVGEIQQNKSVTYDLSKLVNYPGFNISTPRGIPDEWRIFGSIPMQACQQKDVFANYLTSNFQAPGVKSGNK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZCCHC8 Antibody

ZCCHC8 Antibody Immunohistochemistry-Paraffin: ZCCHC8 Antibody [NBP1-85135]

Immunohistochemistry-Paraffin: ZCCHC8 Antibody [NBP1-85135]

Staining of human skeletal muscle shows strong nuclear positivity in myocytes.
ZCCHC8 Antibody Immunohistochemistry-Paraffin: IGSF6/DORA Antibody [NBP1-85135]

Immunohistochemistry-Paraffin: IGSF6/DORA Antibody [NBP1-85135]

Staining of human bone marrow shows strong nuclear positivity in hematopoietic cells.
ZCCHC8 Antibody Immunohistochemistry-Paraffin: ZCCHC8 Antibody [NBP1-85135]

Immunohistochemistry-Paraffin: ZCCHC8 Antibody [NBP1-85135]

Staining of human fallopian tube show strong nuclear positivity in glandular cells.
View 2 more images

Applications for ZCCHC8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1 - 4 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZCCHC8

ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.

Alternate Names

DKFZp434E2220, zinc finger CCHC domain-containing protein 8, zinc finger, CCHC domain containing 8

Gene Symbol

ZCCHC8

Additional ZCCHC8 Products

Product Documents for ZCCHC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ZCCHC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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