SIX5 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-45347

Novus Biologicals, part of Bio-Techne
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NBP3-45347
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SIX5 Antibodies »

Product Specifications

Immunogen

SIX homeobox 5. (Uniprot# Q8N196)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit SIX5 Antibody - BSA Free (NBP3-45347) is a polyclonal antibody validated for use in IHC, WB, ELISA and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for SIX5 Antibody - BSA Free

SIX5 Antibody - BSA Free

Western Blot: SIX5 Antibody - BSA Free [NBP3-45347] -

Western Blot: SIX5 Antibody - BSA Free [NBP3-45347] - Y79 cells were subjected to SDS PAGE followed by western blot with (SIX5 Antibody) at dilution of 1:600
SIX5 Antibody - BSA Free

Immunoprecipitation: SIX5 Antibody - BSA Free [NBP3-45347] -

Immunoprecipitation: SIX5 Antibody - BSA Free [NBP3-45347] - IP Result of anti-SIX5 (IP:, 4ug; Detection: 1:300) with Y79 cells lysate 2000ug.
SIX5 Antibody - BSA Free

Immunohistochemistry: SIX5 Antibody - BSA Free [NBP3-45347] -

Immunohistochemistry: SIX5 Antibody - BSA Free [NBP3-45347] - Immunohistochemistry of paraffin-embedded human kidney tissue slide using (SIX5 Antibody) at dilution of 1:200

Applications for SIX5 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Immunoprecipitation

1:200-1:1000

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 100-105 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SIX5

Six5 (homeobox protein SIX5), also known as SIX5, BOR2 or DMAHP (DM locus-associated homeodomain protein), is a transcription factor that is expressed in various structures of the adult eye. Localized to the cytoplasm in early development and to the nucleus in the later stages of development,Six5 is involved in regulation of organogenesis and in maintenance of retinal formation. Six5 is able to bind the 5'-TCA[AG][AG]TTNC-3' DNA sequence found in the myogenin and IGFBP5 promoters and, through this binding, can control transcription of the associated mRNA. Six5 is regulated via association with DACH1 (dachshund homolog 1) and is co-activated by the EYA (eyes absent) proteins. Defects in the gene encoding Six5 are the cause of branchiooto- renal syndrome type 2 (BOR2), an autosomal disorder characterized by hearing loss, a deep overbite and myopia. Two isoforms exist due to alternative splicing events.

Alternate Names

BOR2, DM locus-associated homeodomain protein, DMAHPsine oculis homeobox homolog 5 (Drosophila), dystrophia myotonica-associated homeodomain protein, homeobox protein SIX5, sine oculis homeobox (Drosophila) homolog 5, Sine oculis homeobox homolog 5, SIX homeobox 5

Gene Symbol

SIX5

Additional SIX5 Products

Product Documents for SIX5 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SIX5 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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