Sin1 is a novel component of the eukaryotic SAPK pathway. Sin1 and the H3 and H4 histones interact genetically, with the C terminus of Sin1 physically associating with components of the SWI-SNF complex. This interaction is blocked by the N-terminal half of the protein in full length Sin1. It has been proposed that Sin1 acts as a regulatable bridge between the SWI-SNF complex and the nucleosome Sin1 is also required for effective transcription via the AP-1 factor Pap1, but does not prevent its nuclear translocation. Sin1 is a novel component of the eukaryotic SAPK pathway.

Long Name

Mitogen-Activated Protein Kinase Associated Protein 1

Alternate Names

JC310, MAPKAP1, MIP1

Gene Symbol

MAPKAP1

Additional Sin1/MAPKAP1 Products

Product Documents for Sin1/MAPKAP1 Antibody (752219) [Janelia Fluor® 525]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Sin1/MAPKAP1 Antibody (752219) [Janelia Fluor® 525]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Sin1/MAPKAP1 Antibody (752219) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # FAB8168JF525

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all Sin1/MAPKAP1 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for Sin1/MAPKAP1 Antibody (752219) [Janelia Fluor® 525]

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Sin1/MAPKAP1