SIGNR3/CD209d Antibody (728804) [Biotin]
Novus Biologicals, part of Bio-Techne | Catalog # FAB7220B
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse, Rat
Applications
Western Blot
Label
Biotin
Antibody Source
Monoclonal Rat IgG2A Clone # 728804
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse SIGNR3/CD209d
Glu82-Lys237
Accession # Q91ZW8
Glu82-Lys237
Accession # Q91ZW8
Specificity
Detects mouse and rat SIGNR3/CD209d in Western blots. In Western blots, 100% cross-reactivity with
recombinant mouse (rm) SIGNR1, 50% cross-reactivity with rmSIGNR7, and no
cross-reactivity with rmSIGNR4 is observed. In direct ELISAs, no cross-reactivity with recombinant human (rh) DC-SIGN, rhDC-SIGNR, rmSIGNR1, rmSIGNR4, or rmSIGNR7 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for SIGNR3/CD209d Antibody (728804) [Biotin]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: SIGNR3/CD209d
SIGNR3 (designated CD209d) is a 237 amino acid, approximately 34 kDa type II transmembrane glycoprotein that is one of several mouse orthologs of human DC-SIGN (CD209). SIGNR3 is a calcium-binding C-type lectin that is expressed on myeloid mononuclear cells and a subpopulation of dendritic cells in the dermis, blood, and most lymphoid organs. Like human DC-SIGN, SIGNR3 recognizes high-mannose and fucose-terminated glycans and protects against pathogens such as Candida albicans and Mycobacterium tuberculosis.
Long Name
DC-SIGN-related Protein 3
Alternate Names
CD209d
Gene Symbol
CD209
Additional SIGNR3/CD209d Products
Product Documents for SIGNR3/CD209d Antibody (728804) [Biotin]
Product Specific Notices for SIGNR3/CD209d Antibody (728804) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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