The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

Long Name

Serpin Peptidase Inhibitor, Clade A, Member 9

Alternate Names

Centerin, GCET1, SERPINA11b

Gene Symbol

SERPINA9

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Product Specific Notices for Serpin A9/Centerin Antibody [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Serpin A9/Centerin Antibody [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # AF5429I

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Background: Serpin A9/Centerin